Horatio Caine, a former homicide detective, heads a group of investigators who work crimes amid the steamy, tropical surroundings and cultural crossroads of Miami. His team includes Calleigh Dusquene, a bilingual Southern beauty with a specialty in ballistics; Ryan Wolfe, and Eric Delko, an underwater recovery expert who knows all the twists and turns of the Florida waterways. Rounding out the team is Alexx Woods, the no-nonsense, know-it-all coroner. Together, these investigators collect and analyze the evidence, solve the crimes, and vindicate those who often cannot speak for themselves the victims.
The investigation of a young woman's murder, reveals a meth lab in her apartment. The team also discovers an unscrupulous FBI agent's secret life.